According to the findings of a recent study, testosterone therapy may have significant benefits for men who display lower levels of the hormone in their system.
The research project was conducted by Dr. Rajat Barua of the VA Medical Center from Kansas City. Together with his research team, Dr. Barua closely analyzed the medical records of as many as 83,010 male subjects. All the study participants were veterans and all of them displayed low testosterone levels, that were confirmed by extensive testing. The term “low testosterone levels” was defined as the minimal quotas included in the normal range of testosterone levels.
In accordance to their their treatment plan and the outcome that was observed, Dr. Barua assigned each of the 83,010 into three separate categories. The first group was that of patients displaying low testosterone levels, but who never received treatment for their condition.
The second group included patients that did receive treatment for their condition, in the form of either gels, patches or injections, but who did not manage to reach a normalization of their hormone levels.
As for the third group, this included the patients who did receive treatment and who also achieved a positive outcome, meaning that they achieved normal hormone levels.
By conducting a vast analysis of their state of health after the hormone treatment for a period of more than 6 years, the research team observed quite a few significant improvements in the men from the third group, for whom the treatment was successful.
It seems that these subjects displayed a 24% lower rate of myocardial infarction and a 36% lower rate of ischemic stroke than the subjects from the first group did, who did not receive treatment for their condition. Overall, they presented a 54% lower rate of early death than the subjects in the first group.
Furthermore, when the subjects from the third group were compared to those in the second group, which included the patients for whom the testosterone treatment was not successful, it seems that they still displayed better outcomes. They had an 18% lower risk of myocardial infarction and a 30% lower risk of ischemic stroke and a 57% lower risk of early death.
“It is the first study to demonstrate that significant benefit is observed only if the dose is adequate to normalize the total testosterone levels” clearly pointed out Dr. Barua.
The improvements in overall health were only seen in men who achieved a normalization of their testosterone levels. Therefore, the testosterone replacement therapy itself did not lead to any positive outcomes, unless the hormone levels were brought to normal rates.
Dr. Barua’s study will bear great importance to medical professionals dealing with men who display symptoms of low testosterone levels, such as exaggerated fatigue and decreased sexual performance. These patients should be tested and if they are diagnosed with low testosterone, then the hormone replacement therapy might greatly improve their lives.
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